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Jennifer A. Doudna
Health & Medicine
Jennifer A. Doudna is an American biochemist whose work on CRISPR-Cas9 genome editing earned her a shared Nobel Prize in Chemistry.
Biography
Jennifer Anne Doudna is an American biochemist working in biochemistry, genetics, and genome editing. She holds the Li Ka Shing Chancellor's Chair Professorship at the University of California, Berkeley, and has been a Howard Hughes Medical Institute investigator since 1997.
In 2012, Doudna and Emmanuelle Charpentier proposed using CRISPR-Cas9 for programmable genome editing. They shared the 2020 Nobel Prize in Chemistry for developing a method for genome editing. Doudna's research on ribozyme structure also earned her the 2000 Alan T. Waterman Award.
Her work includes discussion of the responsibilities surrounding gene editing. In 2015, she called for a worldwide moratorium on using CRISPR to make heritable changes in human embryos. With fellow researcher Samuel Sternberg, she wrote A Crack in Creation about the discovery and its ethical and societal implications.
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Books by Jennifer A. Doudna
A Crack in Creation
A Crack in Creation, written with Samuel Sternberg, recounts Doudna's role in developing CRISPR and explores the potential benefits and risks of rewriting genetic code. It examines the responsibility accompanying gene editing, including the ethical and societal implications of heritable changes in human embryos.